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DeCS
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Descriptor English:
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Transforming Growth Factor beta
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Descriptor Spanish:
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Factor de Crecimiento Transformador beta
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Descriptor Portuguese:
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Fator de Crescimento Transformador beta
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Synonyms English:
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Bone-Derived Transforming Growth Factor
Platelet Transforming Growth Factor
TGF-beta
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Tree Number:
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D12.644.276.374.687
D12.644.276.954.800.720
D12.644.276.963.720
D12.776.467.374.687
D12.776.467.942.800.720
D12.776.467.960.720
D23.529.374.687
D23.529.942.800.720
D23.529.960.720
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Definition English:
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A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins. |
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History Note English:
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91; was see TRANSFORMING GROWTH FACTORS 1989-90; TGF-BETA was see TRANSFORMING GROWTH FACTORS 1989-90
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Allowable Qualifiers English:
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Record Number:
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29139
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Unique Identifier:
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D016212
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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